Use of titanium nitride ceramic materials in biomedicine

Overview of Titanium Nitride

Titanium nitride (TiN) is a very hard ceramic material, usually used as a coating for titanium alloys, steel, carbides and aluminum components to improve the surface properties of the substrate. The Vickers hardness of TiN is 1800-2100, The elastic modulus is 251 GPa, the thermal expansion coefficient is 9.35×10-6 K-1, and the superconducting transition temperature is 5.6K.

Titanium nitride (TiN) has a typical NaCl-type structure, a face-centered cubic lattice, with a constant lattice a = 0.4241nm, in which titanium atoms are located at the corners of the face-centered cubic. TiN is a non-stoichiometric compound, and its stable composition range is TiN0.37-TiN1.16, and the nitrogen content can be changed within a specific range without causing changes in the TiN structure. TiN powder is usually yellow-brown, ultrafine TiN powder is black, and TiN crystals are golden yellow. TiN has a melting point of 2950°C, a density of 5.43-5.44g/cm3, a Mohs hardness of 8-9, and high thermal shock resistance. The melting point of TiN is higher than that of most transition metal nitrides. The density is still lower than most metal nitrides, so it is a very distinctive

Relevant studies have shown that because titanium nitride (TiN) is a material with good biocompatibility (used for coronary stents), the source of thrombus is much lower than that of nickel titanium itself. In response to this medical problem, scientists have developed a Cera ceramic membrane occluder using high-energy ion precipitation coating technology. The occluder maintains the original design on the basis of the original nickel-titanium alloy occluder design. Interval occluder and septal septum occluder. The design of the occluder and patent ductus occluder uses plasma technology to uniformly cover a layer of titanium nitride TiN film on the surface of the nickel-titanium alloy powder. Using ion technology, the metal titanium coating and C, N, O and other compounds are transformed into biofilms. The biological layer significantly improves the corrosion resistance of the occluder and the compatibility of biological tissues and blood. According to the comparison of animal experiment data between Cera ceramic membrane occluder and ordinary Nitinol occluder, it can be seen that Cera ceramic membrane occluder is much better than ordinary Nitinol occluder in terms of cell creep growth performance. It improves the repair of congenital heart defects and significantly reduces the risk of thrombosis; the rate of platelet adhesion and hemolysis is also much lower than that of ordinary nickel-titanium occluders. At present, the Cera occluder has been approved by the European Union, India, Brazil, Russia and other regions and countries.

Application of titanium nitride

The occluder used to treat congenital heart disease of atrial septal defect, ventricular septal defect and patent ductus arteriosus has been widely used as an implant for interventional therapy in clinical medicine. However, the common concentric obturator is mainly made of Nitinol material, in which the nickel content is as high as 55%. Too much nickel can cause allergies and poisoning of the human body, and long-term effects are more likely to induce cancer. The surface purification membrane of the occluder nickel-titanium alloy may be destroyed, and the release of internal nickel ions in the complex environment of the human body will increase the nickel content, which further leads to the deterioration of the histocompatibility of the occluder

The price of titanium nitride

The price of titanium nitride will vary randomly with the production cost, transportation cost, international situation, and market supply and demand of titanium nitride. TankiNew Materials Co. Ltd aims to help all industries and chemical wholesalers find high-quality products by providing a full set of customized services. Services, low-cost nanomaterials and chemicals. If you are looking for titanium nitride, please feel free to send an inquiry to get the latest price.

Suppliers of Titanium Nitride

As a global titanium nitride supplier, Tanki New Materials Co. Ltd has extensive experience in the performance, application and cost-effective manufacturing of advanced and engineered materials. The company has successfully developed a series of powder materials (titanium nitride, silicon nitride, titanium nitride, etc.), high-purity targets, functional ceramics and structural devices, and provides OEM services.

Technical Parameter of Titanium Nitride TiN powder

  
Chemical Composition of Titanium Nitride TiN powder